Three active ingredients protect your roses from insects and diseases: Labda-Cyhalothrin, Thiamethoxan, and Difenoconazole. Thiamethoxan is absorbed by the plant and moves insects from within. Difenoconazole is a contact and systemic fungicide that works in the plant and stops existing diseases from progressing. Labda is a contact insecticide that knocks out insects that are currently present. One application lasts up to 30 days and is rainproof within 1 hour. Mix 3 oz in 1 gallon of water.